In order to investigate the response of yield related traits in three grain corn hybrids to WEED COMPETITION periods, a factorial experiment was conducted in research station of agriculture faculty of Islamic Azad university of Tabriz based on randomized complete block design in three replicates in 2007. The treatments were combination of WEED interference periods (interference until 2–4, 4–6, and 6–8 leaf stages of corn, full season WEED interference and WEED free control plot) and three corn hybrids (504, 604 and 704). Results showed that the traits such as stem height, number of grain row per maize, and grain yield were significantly influenced by corn hybrids, But by WEED interference treatments. Results indicated that biological yield, dry weight of stem, leaf and maize were affected by WEED interference treatments and reduced 25%, 22%, 23% and 32%, respectively in full season WEED interference treatment. 504 Hybrid with stem height of 169 cm, grain yield of 5.8 tha-1 and biological yield 11.6 tha-1 was better than 604 and 704 hybrids. In interference treatments, WEED free control plot showed the best result.